Seeded grapes offer extra health perks over seedless, mainly from their rich antioxidants (proanthocyanins, flavonoids, resveratrol) in the skin and seeds, which boost heart health, fight inflammation, improve circulation (reducing swelling), protect brain function, and offer anti-cancer/anti-diabetic potential by combating oxidative stress.

You need to chew the bitter seeds to unlock these concentrated nutrients, otherwise they pass through undigested.